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The beginning of a pandemic?

 27th April 2009

The Health Protection Agency now says it only a matter of time before the first cases of the new strain of swine flu are confirmed here.

It feels as though the world could be on the brink of something momentous, but no one dare quite imagine that.

It was a little eerie yesterday, as everybody continued to go about their weekend, with the whispered threat of a flu pandemic in the background... The vibes from the experts aren't good. I spoke to Dr John MacCauley, a virologist at the World Influenza Centre in Mill Hill.

His visions of a possible future are some of the darkest.

Remembering, of course, that there are always reasons why such "possible" scenarios might never play out, what he had to say after catching up with colleagues working on the new virus was unnerving. The fact that this virus is showing pretty efficient human-to-human transmission is what worries him.

"I suspect this is what the beginning of a pandemic looks like".

We discussed the WHO pandemic-alert levels - 1 to 6. The world is already sitting at threat level 3 as a result of the H5N1 bird flu that we've come to know (sporadic cases or small clusters of disease in people, but no sustained human-to-human transmission). Tomorrow, the WHO is expected to reassess that level, with the arrival of this Swine Flu virus.

At the weekend it was thought that might rise to 4, but Dr MacCauley thinks the world is already at 5 (human-to-human spread of the virus into at least two countries in one WHO region). Might sound technical, but what that actually means, according to the WHO check list, is a "strong signal that a pandemic is imminent".

Certainly, governments are beginning to react as if that's a possibility. Yesterday, the US mobilised a quarter of its stockpile of anti viral medicines. Dr MacCauley expects we'll do the same here soon.

He talks in unnerving terms about the numbers of "excess deaths". What does that mean?

"It could be anywhere between one million and 50 million. I couldn't really place it along that line."

His laboratory expects to receive samples tomorrow from the US Centers for Disease Control - so that it can create a swift diagnostic kit, learn more about the genetic make up of the new virus, and advise on a possible vaccine.

So are there reasons to be cheerful?

Some. The UK is home to some of the world's leading experts on influenza, and has one of the best pandemic preparedness plans in the world.

The virus appears to be causing only mild symptoms, so far, outside of Mexico. Some of us may have some protection from this new virus because similar H1N1 viruses have circulated in recent decades.

 

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